Here’s a short introduction to the game for both men and women.
The rules are extremely different.

Men’s lacrosse

Field lacrosse is a full contact outdoor men’s sport played with ten players on each team. The sport originated among Native Americans, and the modern rules of field lacrosse were initially codified by Canadian William George Beers in 1867.

Field lacrosse is one of three major versions of lacrosse played internationally. The other versions, women’s lacrosse (established in the 1890s) and box lacrosse (originated in the 1930s), are played under significantly different rules.

The object of the game is to use a lacrosse stick, or crosse, to catch, carry, and pass a solid rubber ball in an effort to score by shooting the ball into the opponent’s goal. The triangular head of the lacrosse stick has a loose net strung into it that allows the player to hold the lacrosse ball. In addition to the lacrosse stick, players are required to wear a certain amount of protective equipment. Defensively the object is to keep the opposing team from scoring and to dispossess them of the ball through the use of stick checking and body contact. The rules limit the number of players in each part of the field. It is sometimes referred to as the “fastest sport on two feet”.

Women’s lacrosse

Women’s lacrosse (or girls’ lacrosse), sometimes shortened to lax, is a sport played with twelve players on each team. Originally played by indigenous peoples of the Americas, the modern women’s game was introduced in 1890 at the St Leonard’s School in St Andrews, Scotland.

The rules of women’s lacrosse differ significantly from men’s field lacrosse. The object of the game is to use a long-handled stick (known as a lacrosse stick) to catch, cradle, and pass a solid rubber lacrosse ball in an effort to score by hurling the ball into an opponent’s goal.

The head of the lacrosse stick has a mesh or leather net strung into it that allows the player to hold the ball. Defensively the object is to keep the opposing team from scoring and to dispossess them of the ball through the use of stick checking and body positioning.

The rules of women’s lacrosse are different from the men’s lacrosse game. Equipment required to play is also different from the men’s. Internationally, women are required to wear a mouthguard, and have the option to play without protective goggles. The stick has restrictions too, as it must be a certain length and the pocket must be shallow enough to show the ball above the side when held at eye level.

Source: https://en.wikipedia.org/wiki/Women%27s_lacrosse#Rules
Source: https://en.wikipedia.org/wiki/Field_lacrosse